The article presents the results of our own research on helminth infestation of cattle, elk, red deer, Sika deer and fallow deer. The effectiveness of the veterinary drug «Triclamizole» in associative helminthiasis of cattle and wild ruminants was studied and determined. The drug in a dose of 75 mg/kg of body weight once inside is effective for trematodoses, nematodoses by 93-100 %.
For diagnosis of anaplasmosis use various methods, such as microscopic and serological. The decisive factor in diagnosis is a positive result of microscopic examination of blood smears stained according to Romanovsky. Molecular biological methods have got high diagnostic sensitivity. They are interest to researchers. The development and optimization of these methods is promising for use in veterinary practice.
In the course of the studies, it was found that in fur animals and wild ungulates in the acute and chronic periods of the myxparasitic process, proceeding without intoxication and accompanied by the development of intoxication, significant differences in the qualitative and quantitative characteristics of the immune.
An analysis of the mouse-like rodent community in various undeveloped areas of Minsk was carried out. The main changes in the species composition and number of mouse-like rodents depending on the degree of recreational load on the green areas of the city have been revealed.
The analysis of the annual dynamics of the population of Apodemus (Sylvaemus) flavicollis Melchior 1834 in the city of Minsk was carried out. The annual dynamics of the number of helminths Apodemus (Sylvaemus) flavicollis was studied. The features of changes in the number of helminths of various ecological groups in the urban area have been revealed.
In the course of the studies, it was found that the proposed methods for improving the health and increasing the sustainability of resource species of wild ungulates and fur animals are highly effective. These methods include the firstly developed samples of drugs and feed additives and take into account the species characteristics and feed preferences of animals.
The article presents data on associations of virus and bacterial genomes secreted by the method ofpolymerase chain reaction from lungs ofpigs with signs of respiratory system damage. It is established that in all three farms respiratory pathology is caused by viral and bacterial pathogens. The genome of the causative agent Haemophilus parasuis was found in three of the three households, as well as the genome of the pathogen Bordetella bronchiseptica and the genome of the pathogen of circovirus type II and PRRS. In two of the three farms, we isolated the genomes of the pathogens Steptococcus suis, Parvovirus suis. Only in one farm (farm 3) the Actinobacillus pleuropneumoniae pathogen genome was isolated.
The article provides an analysis of the epizootic situation of rabies in the Republic of Belarus, as well as the sequence of applied developments and technologies in the field of design of rabies vaccines for animals and the results of the effectiveness of the developed blisters vaccine-containing rabies vaccine virus, which in experimental tests has indicators of high efficiency, safety and is promising in practical application.
The article provides data on rabbit pasteurellosis. It is known that mortality from pasteurellosis can range from 15 % to 75 %. Therefore, the source can be not only a sick rabbit, but also a sick rabbit.
The article presents the results of research on the study of the actual time of excretion of colistin after the using of veterinary drugs «Colistin-О», «Kolistin Aqua» and «Koli 12-TRV» on broiler chickens to establish the waiting period. Tests have shown that the content of colistin in poultry meat on the day of discontinuation of the use of the studied veterinary drugs does not exceed the maximum allowable level of residues. The research results allowed the manufacturers of these veterinary drugs to amend the instructions for use and reduce the waiting period from 7 days to 1 day.
The article presents data on the study of toxicity and safety of new feed additives «LauriTan», «ButyTan» based on а-monoglycerides. It was established that «LauriTan» and «ButyTan» belong to the IV class of hazard - low-hazard substances and are harmless to the protozoa Tetrachimena piriformis.
The article deals with the toxicity, without the biological value of sodium bicarbonate, as well as its effect on the quality of animal origin.
An antiparasitic drug of broad spectrum based on prasicuantel, ivermectin and arabinagalactan has been developed. Its extensive efficiency for intestinal parasitoses of horses in a comparative analysis widely used antihelmintic drugs has been studied. A high efficiency is established with a persistent activity of 2,5 montls.
The article presents data on the development of a system for assessing the content of lactate dehydrogenase in milk for the early diagnosis of cow mastitis. the dependence in cow milk between the content of somatic cells in 1 cm3 and the activity of lactate dehydrogenase in milk is revealed. Thus, with an increase in the content of somatic cells in 1 cm3 to a level of 500 thousand and higher (subclinical mastitis), the activity of lactate dehydrogenase in milk increases over 200 U/l. The data obtained indicate that it is possible to assess the risk of breast inflammation by the activity of lactate dehydrogenase in milk.