In the course of the studies it was found that against the background of wild boar depopulation, the population density of deer and roe deer increases. Species do not compete in the original communities of the ungulates because they don’t have adaptive advantages. Some species are able to dominate in the newly formed communities. An increase in population density affects the protective and adaptive reactions of wild ungulates. In conditions of ecological optimum and pessimism the development of resistance of wild ungulates is characterized by phases.

Dissemination of red deer has been carried out in the game farms of the Belarusian Society of Hunters and Fishers Since 2014. It was possible to significantly increase the animals number of this species thanks to this initiative. Viable populations of red deer have formed in many game farms. The success of this process is largely determined by the assessment of the epizootic situation of parasitoses, as well as the implementation of preventive measures using anthelmintic drugs with a wide spectrum of action with an immunostimulating effect.

Studies have found that the number of reported species of helminthes in wild ungulates varies at different seasons of the year: during the summer-autumn season - 12 species of helminthes, the winter-spring - 16 species. Helminthes, as a biotic factor, has a strong impact on the organisms’ resistance of wild ungulates. The finding of resistance indicators of animals allows determining the degree of unfavorable biotic environmental factors (helminthes) exposure and to assess the resistance of both individual organisms and the population as a whole

In the fauna of ectoparasites of chickens and chickens of different ages in modern poultry farms, the dominant bloodsucking mites are Dermanyssus gallinae, sometimes Ornithonyssus sylvarum is found. When an intense attack causes the disease «Dermanissiosis», characterized by anxiety, anemia, hemorrhages, decreased productivity, hemostasis disorders. For treatment, it is recommended to use antitoxic and immunostimulating agents. Effective aczolt to destroy dermanyssus.

Cestodoses are often recorded helminthic diseases and represent a serious problem for veterinary and human medicine. The circulation of cestodosespathogens is caused not only by the biology of the parasites, but also by short-comings in the system of diagnostic, sanitary and veterinary measures for the maintenance and breeding of domestic animals, including dogs. Currently relevant are the issues of finding new and optimizing forms of known drugs for the treatment and prevention of imaginal cestodoses carnivorous. The study reveals the efficiency of using Prazitexum-5 at a dose of 5 mg/kg of body weight subcutaneous for the treatment of dogs against the imaginal cestodes (Taenia pisiformis, T. hydatigena, Dipylidium caninum).

The article first studied the morphological study of the endocrine glands and the biochemical study of the blood of an Eastern European hedgehog in the stressful period after hibernation (in the conditions of the Belarus range). The prophylactic effect of the «Calcemagphosvit» drug against metabolic disorders and stressful situations in hedgehogs is proved. Prevention of stressful effects (awakening after hibernation) is one of the main ways to improve the health of the hedgehog.

The paper presents data on the most common рathomorphology nephrosis in animals. A description of state at the macroscopic kidney nephrosis and microscopic manifestations of this disease.

This article provides an overview of in vitro research methods that are alternative to in vivo experiments. The problems of animal experiments are considered. It is shown that alternative methods are widely used in scientific practice to determine the toxicity of substances

Cell wall deficient (CWD) mycobacteria of tuberculosis is isolated from culture of cells of cervical adenocarcinoma (HeLa). The isolate exhibited «immortality» and restored bacterial form after chemical inactivation, ultrasonic destruction, removal of detritus and molecules larger than 100 kDa and 3 kDa, giving growth of cells almost not different not only from initial cells, but also from CWD M. tuberculosis H37Rv. Isolates were sensitive only to fluoroquinolones, did not cause obvious disease in guinea pigs, but induced development in organs of microgranulems with acidfast grains. It is suggested that mycobacteria of tuberculosis by infecting cells, can persistance in them in an unusual form, possibly integrating fragments of genome into the host DNA and under certain conditions, turning them into cancer at the expense of their unusual properties.

The effectiveness of use of cattle adipose tissue-derived mesenchymal stem cells (MSCs) for a treatment of purulent-necrotic diseases of hooves and finger of dairy cattle was studied. The results of clinical trials indicate that the treatment with adipose tissue-derived MSCs of lesion site of cattle hooves with the presence of appropriate diseases accelerates the formation of healthy granulation tissue and reduces the healing time of wound defects by 5-8 days compared with the treatment based on the use of basic therapeutic drugs used in dairy farming.

The article presents data on microorganisms isolated from the respiratory tract of piglets with signs of bronchopneumonia, their morphological characteristics and serotyping. It was found that in 15.9 % of the pathological material Actinobacillus pleuropneumoniae of serotypes 2, 3, 5, 6, 9, 10 is excreted. In 50 % of cases, the causative agent of actinobacillary pneumonia of serotypes 2, 6 was isolated. The frequency of isolation of Actinobacillus pleuropneumoniae from the studied material in the context of farms was slightly different. Most often, the pathogen was isolated from the material of farms in the Minsk region 40 %, respectively, whereas in one of the farms of the Grodno region, the pathogen was isolated only in 16.3 % of cases.

An assessment of the spread of viral respiratory diseases and pneumoenteritis in calves and their impact on the main blood parameters of animals is given. The results of application of the drug based on nanoparticles of zinc «Immunoenhancing» in a production environment.